It's takes no stretch of the imagination to come to the general conclusion that the number of heavy hits professional football players take are hazardous to their health. The Center for the Study of Traumatic Encephalopathy has studied the brains of 5 former NFL players after their (early) deaths and discovered brain damage that's commonly associated with boxers. Twelve professional athletes, including six NFL players, have agreed to donate their brains to the center after their deaths to help the center with its study of the long-term effects of concussions, which published studies connect with cognitive impairment and depression. The NFL says that "in regard to its players, the long-term effects of concussions are uncertain." [NYT]
injuries come with the territory.
Having played football in HS, I can say that even at that level, the hits and mental toll it took on me and my teammates was pretty bad. Also you have to consider that some people start playing as early as 7-8 years old and if they're good enough can play until their mid to late 30's. That's a lotta damage the human body isn't made to take no matter what the physical makeup of a player is.